he in vivo local delivery of regulatory cytokines made possible by gene therapy is becoming an exciting approach for treating common disorders such as cancer and viral infections I. Recently, gene therapy strategies have been applied to the treatment of autoimmune diseases. Cells targeted for autoim
β¦ LIBER β¦
Assessing the Role of Gene Therapy in the Treatment of Vascular Disease
β Scribed by Peter L. Faries; Frank B. Pomposelli Jr.; William C. Quist; Frank W. LoGerfo
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 250 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0890-5096
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Normal arteries are characterized by a low turnover of endothelial (EC) and smooth muscle cells (SMC). Different mechanisms protect the EC and SMC against apoptosis in the normal artery. In hypertension, SMC replication is increased but this is not counterbalanced by increased apoptosis, resulting i