๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Assessing the protease and protease inhibitor content of the human genome

โœ Scribed by Christopher Southan


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
65 KB
Volume
6
Category
Article
ISSN
1075-2617

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Protease inhibitors and carcinoma of the
โœ Alastair M. Sammon ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 64 KB ๐Ÿ‘ 2 views

## Background: Squamous cell carcinoma of the esophagus is endemic in parts of south africa. previous case-control studies have shown many associations but no clear etiologic pathway has been established. ## Methods: A case-control study of dietary and social factors was performed for 130 patient

The Ex Vivo human placental transfer of
โœ R.E. Bawdon ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Hindawi Publishing Corporation ๐ŸŒ English โš– 52 KB ๐Ÿ‘ 1 views

## Objective: The transfer of abacavir, a new nucleoside inhibitor, and amprenavir, a new protease inhibitor, used for the treatment of human immunodeficiency virus, has been studied in the ex vivo human placental model. ## Methods: The ex vivo human placental model used c14 antipyrine to determi

The Conformation of a Peptidyl Methyl Ke
โœ Steven R. LaPlante; Dale R. Cameron; Norman Aubry; Pierre R. Bonneau; Robert Dรฉz ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 148 KB ๐Ÿ‘ 1 views

A weak inhibitor means faster exchange! Since the methyl ketone MK2 is a weak noncovalent peptidyl inhibitor of the human cytomegalovirus protease, exchange between the free and enzyme-bound forms is rapid. This allows for the use of transferred NOE NMR methods and molecular modeling, which show tha

Design of protease inhibitors on the bas
โœ Dong H. Kim ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 77 KB ๐Ÿ‘ 1 views

The substrate stereospecificity in enzymic reactions, which is one of characteristics of enzymes along with the substrate and regiospecificity can provide a basis for the rational design of inhibitors. This has been demonstrated using โฃ-chymotrypsin, a prototypic serine protease as a model enzyme. O

The effect of inhibitor binding on the s
โœ Matthew J. Todd; Ernesto Freire ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 337 KB ๐Ÿ‘ 2 views

The effects of the peptide inhibitor acetyl pepstatin on the structural stability of the HIV-1 protease have been measured by high sensitivity calorimetric techniques. At 25ยฐC and pH 3.6, acetyl pepstatin binds to HIV-1 protease with an affinity of 1.6 ุ‹ 10 7 M -1 and an enthalpy of 7.3 ุŽ 0.5 kcal/m