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Assessing the dose-dependency of allometric scaling performance using physiologically based pharmacokinetic modeling

โœ Scribed by C.R Kirman; L.M Sweeney; M.E Meek; M.L Gargas


Book ID
116991652
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
733 KB
Volume
38
Category
Article
ISSN
0273-2300

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## Abstract Physiologically based pharmacokinetic (PBPK) models are sophisticated dosimetry models that offer great flexibility in modeling exposure scenarios for which there are limited data. This is particularly of relevance to assessing human exposure to environmental toxicants, which often requ