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Assessing RNA quality in postmortem human brain tissue

✍ Scribed by Ia Chevyreva; Richard L.M. Faull; Colin R. Green; Louise F.B. Nicholson


Book ID
113956550
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
438 KB
Volume
84
Category
Article
ISSN
0014-4800

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The ability to isolate intact RNAs from postmortem human brain permits analysis of gene expression and may help uncover the nature of the molecular lesions in neurological diseases. Starting with poly(A) RNA from postmortem brain of neurologically normal patients, we have constructed two complementa