Assessing grip strength in healthy individuals and patients with immune-mediated polyneuropathies

Evaluation of CD8+ T-cell frequencies by

Evaluation of CD8+ T-cell frequencies by the Elispot assay in healthy individuals and in patients with metastatic melanoma immunized with tyrosinase peptide

✍ Jonathan J. Lewis; Sylvia Janetzki; Susanne Schaed; Katherine S. Panageas; Siqun 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 172 KB 👁 1 views

The lack of reproducible, quantitative assays for T-cell responses has been a limitation in the development of cancer vaccines to elicit T-cell immunity. We utilized the Elispot assay, which allows a quantitative and functional assessment of T cells directed against specific peptides after only brie