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Assembly of N , N -Disubstituted Hydrazines and 1-Aryl-1 H -indazoles via Copper-Catalyzed Coupling Reactions

✍ Scribed by Xiong, Xiaodong; Jiang, Yongwen; Ma, Dawei


Book ID
111645537
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
590 KB
Volume
14
Category
Article
ISSN
1523-7060

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Synthesis of 1-aryl-1H-indazoles via the
✍ Jinhua J Song; Nathan K Yee πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 72 KB

1-Aryl-1H-indazoles were synthesized by the palladium-catalyzed intramolecular amination [Pd(OAc) 2 /dppf/tBuONa (150 mol%)/toluene/90Β°C] of the corresponding N-aryl-N%-(o-bromobenzyl)hydrazines. It was further demonstrated that cyclization of [N-aryl-N%-(o-bromobenzyl)-hydrazinato-N%]-triphenylphos