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Assembly of infectious hepatitis C virus particles

✍ Scribed by Ralf Bartenschlager; Francois Penin; Volker Lohmann; Patrice André

Book ID
116917568
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
728 KB
Volume
19
Category
Article
ISSN
0966-842X

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Chronic hepatitis C virus (HCV) infection is a major cause of liver disease worldwide. Restriction of HCV infection to human hepatocytes suggests that liver-specific host factors play a role in the viral life cycle. Using a yeast-two-hybrid system, we identified apolipoprotein E (apoE) as a liver-de