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Assays for enhanced activity of low efficacy partial agonists at the D2 dopamine receptor

✍ Scribed by H Lin; S G N Saisch; P G Strange


Book ID
110009255
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
168 KB
Volume
149
Category
Article
ISSN
0007-1188

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Herein, we evaluate the interaction of the ␣ 2 -AR antagonist, yohimbine, as compared to fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of adrenergic, dopaminergic and serotonergic transmission in freelymoving rats. Yohimbine displays marked affinity at hum