A correlation between three molecular connectivity indexes and the muscarinic receptor affinity of 104 acetylcholine antagonists was found. Analysis of structure from these indexes reveals not only the importance of the onium and the bulky portions of the molecule but also their virtual independence
Assay of the acetylcholine receptor by affinity labeling
✍ Scribed by Arthur Karlin; Mark G. McNamee; David A. Cowburn
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 599 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0003-2697
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