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Assay of hyoscyamine, atropine, scopolamine, and phenobarbital in unit doses of tablets and elixirs

โœ Scribed by Rupert O. Zimmerer Jr.; Lee T. Grady


Publisher
John Wiley and Sons
Year
1970
Tongue
English
Weight
385 KB
Volume
59
Category
Article
ISSN
0022-3549

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A signal transduction pharmacodynamic mo
โœ Itay Perlstein; David Stepensky; Wojciech Krzyzanski; Amnon Hoffman ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 142 KB

We used a novel pharmacokinetic-pharmacodynamic (PK-PD) approach that had been applied for signal transduction kinetics to investigate the kinetics of the parasympathomimetic effect of scopolamine and atropine in rats. The parasympathetic tone was assessed by continuous measurement of the power of t