Assay of benzenoid drugs in tablet and capsule formulations by second-derivative ultraviolet spectrophotometry

Determination of low levels of phenothia

Determination of low levels of phenothiazine sulphoxides in phenothiazine drug substances and formulations by thin-layer chromatography-second-derivative spectrofluorimetry

✍ E.O. Fadiran; A.G. Davidson 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 593 KB

A thin-layer chromatographic-second derivative spectrofluorimetric procedure has been developed for low levels of sulphoxide (down to O.Ol%, w/w) in phenothiazine drug substances and formulations. The method has been applied to prochlorperazine maleate, chlorpromazine hydrochloride and promethazine