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Assay for methylnaltrexone in rat brain regions and serum by high-performance liquid chromatography with coulometric electrochemical detection

โœ Scribed by C. Kim; R. Cheng; W. A. Corrigall; K. M. Coen


Book ID
112719875
Publisher
Springer
Year
1989
Tongue
English
Weight
361 KB
Volume
28
Category
Article
ISSN
0009-5893

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โœ L. G. Harsing Jr.; A. Lajtha; E. S. Vizi ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 348 KB

The release and content of the excitatory amino acid neurotransmitters glutamate and aspartate in rat striatum were determined by liquid chromatography/electrochemistry. This determination was based on precolumn off-line derivatization of the amino acids with o-phthaldialdehyde and 2-mercaptoethanol