𝔖 Bobbio Scriptorium
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Aspects of the mechanisms of action of biguanides on trophozoites and cysts of Acanthamoeba castellanii

✍ Scribed by W. Khunkitti; D. Lloyd; J.R. Furr; A.D. Russell

Book ID
108837419
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
575 KB
Volume
82
Category
Article
ISSN
1364-5072

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Acanthamoeba rRNA transcription involves the binding of a transcription initiation factor (TIF) to the core promoter of rDNA to form the preinitiation complex. This complex is formed in the absence of RNA polymerase I, and persists for multiple rounds of initiation. Polymerase I next binds to form t