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Aspects of molecular phenotype and its correlations with breast cancer behaviour and taxonomy

✍ Scribed by Hanby, A M


Book ID
109998422
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
84 KB
Volume
92
Category
Article
ISSN
0007-0920

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It is clear that breast cancer progression is associated with inactivation of a number of different recessive oncogenes. The most widely evaluated tumor suppressor gene, p53, is mutated in approximately 30-50% of sporadic breast cancers. Mutations usually occur early in malignant progression. Loss o