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Aspects of cellular physiology that influence DNA-mediated gene transfer in NIH3T3 cells

โœ Scribed by James T. Reston; Susan Gould-Fogerite; Raphael J. Mannino


Book ID
105011075
Publisher
Springer
Year
1995
Tongue
English
Weight
702 KB
Volume
145
Category
Article
ISSN
0300-8177

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We transduced mouse cytochrome P4501A2 DNA into NIH 3T3 cells by retrovirus-mediated gene transfer. The capacity of the transduced cytochrome P4501A2 for metabolic activation and DNA-carcinogen adduct formation of aromatic amine carcinogens was investigated. Clones of NIH 3T3 cells that constitutive