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Asparaginyl endopeptidase: case history of a class II MHC compartment protease

✍ Scribed by Colin Watts; Stephen P. Matthews; Daniela Mazzeo; Bénédicte Manoury; Cathy X. Moss


Book ID
110746624
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
564 KB
Volume
207
Category
Article
ISSN
0105-2896

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## Abstract Whether specific proteases influence MHC class II antigen presentation is still not clearly defined. Cathepsin D, one of the most abundant lysosomal proteases, is thought to be dispensable for MHC class II antigen presentation, yet __in vitro__ digestions of antigen substrates with endo