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ASH2L: alternative splicing and downregulation during induced megakaryocytic differentiation of multipotential leukemia cell lines

โœ Scribed by Junhua Wang; Yan Zhou; Bin Yin; Guangwei Du; Xiaowei Huang; Guangtao Li; Yan Shen; Jiangang Yuan; Boqin Qiang


Book ID
105797589
Publisher
Springer
Year
2001
Tongue
English
Weight
312 KB
Volume
79
Category
Article
ISSN
0946-2716

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Differentiation of the megakaryocytic leukemia cells, CMK, was induced by longterm (1 2 day) treatment with the combination of IL-3 and the nucleoside analogue ribavirin (RV), which reduces cellular GTP levels. In a previous report we demonstrated the induction of early messages and antigens, as wel