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Ascorbic acid treatment corrects the phenotype of a mouse model of Charcot-Marie-Tooth disease

✍ Scribed by Passage, Edith; Norreel, Jean Chrétien; Noack-Fraissignes, Pauline; Sanguedolce, Véronique; Pizant, Josette; Thirion, Xavier; Robaglia-Schlupp, Andrée; Pellissier, Jean François; Fontés, Michel

Book ID
109931572
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
639 KB
Volume
10
Category
Article
ISSN
1078-8956

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## Abstract Expression profiling was performed on sciatic nerve of normal mice and of transgenic mice overexpressing the peripheral myelin protein 22 kDa (PMP22). These mice represent a model for the hereditary peripheral neuropathy Charcot‐Marie Tooth type 1A. Comparison of the profiles reveals th