𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Ascorbate stimulation of salicylate absorption in isolated rat intestine

✍ Scribed by Gene Barnett; Thomas Lockwood; Aquiles Arancibia; Leslie Z. Benet

Book ID
102403951
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
388 KB
Volume
67
Category
Article
ISSN
0022-3549

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✦ Synopsis

Salicylate transport across the rat intestine was measured using both in vitro and in vivo procedures. After the steady state for labeled salicylate was reached, the addition of ascorbate stimulated tracer flux with the establishment of a new steady state. The tissue permeability had a saturable dependence on ascorbate concentration. Also, ascorbate stimulated the tissue short-circuit current.

πŸ“œ SIMILAR VOLUMES

INTESTINAL ABSORPTION KINETICS OF AMIODA
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✍ R. V. MARTÍN-ALGARRA; R. M. PASCUAL-COSTA; M. MERINO; V. G. CASABΓ“ πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 126 KB πŸ‘ 2 views

Amiodarone is a widely used antiarrhythmic agent with highly variable therapeutic eects. These seem to be related, at least in part, to the pharmacokinetics of the drug and particularly to some features of its gastrointestinal absorption process. The drug exhibits physico-chemical properties highly