Ascorbate potentiates amphetamine-induce
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R. Christopher Pierce; James K. Rowlett; George V. Rebec; Michael T. Bardo
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Article
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1995
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Elsevier Science
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English
β 631 KB
In order to evaluate the effects of ascorbate, which is known to modulate dopamine neurotransmission, on the reinforcing effects of amphetamine, we coadministered ascorbate and amphetamine during the acquisition of conditioned place preference (CPP) in rats. Our results indicate that 100 mg/kg ascor