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Asbestos-body formation in the lungs of rats and guinea-pigs after inhalation of anthophyllite

✍ Scribed by Susan K. Botham; P. F. Holt

Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
986 KB
Volume
107
Category
Article
ISSN
0022-3417

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The novel potassium channel activator BRL 55834 and the prototype compound levcromakalim have been compared as inhaled bronchodilators in guinea-pigs and rats. Salbutamol was included in the guinea-pig studies. In anaesthetized guinea-pigs, inhaled BRL 55834 [ED50 = 0.9 (0.5-1.5) micrograms per anim