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AS3MT gene polymorphism in residents exposed to inorganic arsenic via drinking water

✍ Scribed by Ela Kadioglu; N. Deniz Hisarli; Elif Asik; Gonca Cakmak Demircigil; Usama Alshana; Nusret Ertas; Celalettin R. Celebi; Esref Atabey; O. Yavuz Ataman; Hakan Serce; Nazmi Bilir; A. Murat Tuncer; Sema Burgaz


Book ID
116925291
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
87 KB
Volume
211
Category
Article
ISSN
0378-4274

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## Abstract Arsenic is well established as a human carcinogen, but its precise mechanism of action remains unknown. Arsenic does not directly damage DNA, but may act as a carcinogen through inhibition of DNA repair mechanisms, leading indirectly to increased mutations from other DNA damaging agents