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Aryl hydrocarbon receptors in urogenital sinus mesenchyme mediate the inhibition of prostatic epithelial bud formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin

✍ Scribed by Kinarm Ko; Robert W Moore; Richard E Peterson

Book ID: 113923277
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 257 KB
Volume: 196
Category: Article
ISSN: 0041-008X
DOI: 10.1016/j.taap.2003.12.004

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## Abstract Epidemiological and laboratory studies suggested that exposure to 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD) affects glucose homeostasis and increases the incidence of type 2 diabetes mellitus. To evaluate the effects of TCDD on insulin secretion from islets of Langerhans (islets),