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Aryl hydrocarbon receptor-mediated suppression of GH receptor and Janus kinase 2 expression in mice

✍ Scribed by Manabu Nukaya; Yoshiki Takahashi; Frank J Gonzalez; Tetsuya Kamataki


Book ID
117106203
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
229 KB
Volume
558
Category
Article
ISSN
0014-5793

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## Abstract Epidemiological and laboratory studies suggested that exposure to 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD) affects glucose homeostasis and increases the incidence of type 2 diabetes mellitus. To evaluate the effects of TCDD on insulin secretion from islets of Langerhans (islets),