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Aryl hydrocarbon receptor-mediated disruption of contact inhibition is associated with connexin43 downregulation and inhibition of gap junctional intercellular communication

✍ Scribed by Zdeněk Andrysík, Jiřina Procházková, Markéta Kabátková…


Book ID
120747661
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
611 KB
Volume
87
Category
Article
ISSN
0340-5761

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## Abstract Many studies have correlated reductions in gap junctional intercellular communication (a) with altered cellular growth, tumor promotion, and neoplastic transformation. To test directly whether reduced GJIC affects cellular growth, GJIC was inhibited in murine BALB/c 3T3 fibroblasts by t