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Aryl hydrocarbon receptor interacting protein (AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas

✍ Scribed by Marianthi Georgitsi; Ernesto De Menis; Salvatore Cannavò; Markus J. Mäkinen; Karoliina Tuppurainen; Paolo Pauletto; Lorenzo Curtò; Robert J. Weil; Ralf Paschke; Grzegorz Zielinski; Anna Wasik; Jan Lubinski; Pia Vahteristo; Auli Karhu; Lauri A. Aaltonen


Book ID
108704143
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
164 KB
Volume
69
Category
Article
ISSN
0300-0664

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✍ Susana Igreja; Harvinder S. Chahal; Peter King; Graeme B. Bolger; Umasuthan Srir 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 458 KB

Familial isolated pituitary adenoma (FIPA) is an autosomal dominant condition with variable genetic background and incomplete penetrance. Germline mutations of the aryl hydrocarbon receptor interacting protein (__AIP__) gene have been reported in 15–40% of FIPA patients. Limited data are available o