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Aryl hydrocarbon receptor (AhR)-mediated induction of CYP1A1 in human hepatocytes by furanochromones visnagin and khellin

✍ Scribed by Vrzal, Radim; Haarmann-Stemmann, Thomas; Frauenstein, Katrin; Dvorak, Zdenek

Book ID: 122573217
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 80 KB
Volume: 221
Category: Article
ISSN: 0378-4274
DOI: 10.1016/j.toxlet.2013.05.113

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## Abstract The aryl hydrocarbon receptor (AhR) is a receptor/transcription factor which regulates cytochrome P450 (__CYP__) gene transcription and which is activated by environmental carcinogens, some of which are associated with increased breast cancer risk. Here, we show that the AhR is over‐exp

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