Aryl, Alkyl Bis-Silyl Ethers: Rapid Access to Monoprotected Aryl Alkyl and Biaryl Ethers.

✍ Scribed by Sudha V. Ankala; Gabriel Fenteany

• Publisher: John Wiley and Sons
• Year: 2003
• Weight: 132 KB
• Volume: 34
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.200333090

✦ Synopsis

Aryl, Alkyl Bis-Silyl Ethers: Rapid Access to Monoprotected Aryl Alkyl and Biaryl Ethers. -Simple one-pot reaction conditions are reported for the selective conversion of aryl silyl ethers (I) to alkyl aryl ethers (III) or unsymmetrical bisaryl ethers (V) without affecting present siloxyalkyl groups. The method is used to prepare the advanced intermediate (VIII) of cambrestatin synthesis. -(ANKALA,