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Artocarpol A stimulation of superoxide anion generation in neutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways

✍ Scribed by Yu-Hsiang Kuan; Ruey-Hseng Lin; Lo-Ti Tsao; Chun-Nan Lin; Jih-Pyang Wang


Book ID
110008718
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
377 KB
Volume
145
Category
Article
ISSN
0007-1188

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## Abstract Blood vessel injury results in limited oxygen tension and diffusion leading to hypoxia, increased anaerobic metabolism, and elevated production of acidic metabolites that cannot be easily removed due to the reduced blood flow. Therefore, an acidic extracellular pH occurs in the local mi