Meckel–Gruber syndrome associated with R
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As. Prof. Emmanuel Agapitos; Constantinos Christodoulou
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Article
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1995
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John Wiley and Sons
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English
⚖ 445 KB
Meckel-Gruber syndrome, also known as dysencephalia splachnocystica, was originally described by Meckel in 1822, later by Gruber, and more recently by Opitz and Howe. More than 50 cases of this severe disorder have been reported.' This syndrome is characterized by microcephaly secondary to cerebral