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Artifactual phosphate binding due to impurities in [32P]orthophosphate

✍ Scribed by Ralph J. Kessler; Duke A. Vaughn; Darrell D. Fanestil

Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 127 KB
Volume: 158
Category: Article
ISSN: 0003-2697
DOI: 10.1016/0003-2697(86)90598-1

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✦ Synopsis

Many commercial preparations of [32P]orthophosphate contain radioactive impurities that interfere with binding and transport studies in biological systems. One type of impurity is micro-particulate whereas another may be pyrophosphate. Methods of removing these impurities from radiolabeled orthophosphate solutions are described.

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