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Artifact production in the assay of anhydroecgonine methyl ester in serum using gas chromatography–mass spectrometry

✍ Scribed by Stefan W. Toennes; Anabel S. Fandiño; Franz-Josef Hesse; Gerold F. Kauert


Book ID
108497500
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
133 KB
Volume
792
Category
Article
ISSN
1873-376X

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A method has been developed for the blood level determination of the antihypertensive agent tiamenidine hydrochloride. The serum samples are mixed with deuterium labelled tiamenidine hydrochloride as an internal standard and extracted with methylene chloride. The extracts are derivatized with heptaf