Arthroscopic implantation of a three dimensional scaffold for autologous chondrocyte transplantation
โ Scribed by Wolf Petersen; Sandra Zelle; Thore Zantop
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 215 KB
- Volume
- 128
- Category
- Article
- ISSN
- 1434-3916
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## Abstract Articular (medial femoral condyle) and auricular cartilage (anithelix) was compared as a cell source for the autologous joint repair. Cells isolated from five human cadaveric donors were cultured parallel in the monolayer cultures and in the 3D alginate hydrogel constructs for 1 week. C
Sheep articular chondrocytes were cultured for 3, 6, and 9 weeks on a three-dimensional porous scaffold from poly(L/DL-lactide) 80/20%. Cell growth and activity was estimated from the amount of proteoglycans attached to the polylactide scaffold and the amounts of DNA and proteins measured in the cel
## Abstract The promising potential of a RADโ16 selfโassemblyโpeptide hydrogel as a scaffold for tissueโengineered cartilage was investigated. Within 3 weeks of in vitro culture, chondrocytes within the hydrogel produced a high amount of GAG and typeโII collagen, which are the components of cartila