Minor disulfide-bonded collagen (previously termed XI -X7 and now called type IX collagen) was isolated from foetal calf cartilage after pepsin treatment. At least three native fractions, containing, respectively, the xlx2x3, &, and xsx6x7 chains, were separated; and from further biochemical and phy
Arthritogenicity of minor cartilage collagens (types IX and XI) in mice
β Scribed by Marie-Christophe Boissier; Gilles Chiocchia; Marie-Claire Ronziere; Daniel Herbage; Catherine Fournier
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 796 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0004-3591
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This review summarizes the data on 278 different mutations found to date in the genes for types I, II, III, IX, X, and XI collagens from 317 apparently unrelated patients. A majority (217 mutations; 78% of the total) of the mutations are single-base and either change the codon of a critical amino ac
## Abstract ## Objective To examine the pathogenetic mechanisms of osteoarthritis (OA)βlike changes in Col9a1^β/β^ mice, which are deficient in type IX collagen. ## Methods Knee joints and temporomandibular joints (TMJs) from Col9a1^β/β^ mice and their wildβtype (Col9a1^+/+^) littermates were ex
Antibodies to native types I, 11, TX, and XI collagen were measured, using a 'L51-solid-phase radioimmunoassay, in serum from 104 patients with rheumatic diseases (rheumatoid arthritis, osteoporosis, Paget's disease, or osteoarthritis). In all disease groups, antibodies to type 11 collagen occurred