Arterialization of the liver. II. Systemic pressure gradients in rats following variously sized arteriovenous fistulae
✍ Scribed by Edmund Glassford; Milbhor D'Silva; Hussein Ghorab; San Bai; Sang Un Lee; A. R. Moossa; Sun Lee
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 554 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0738-1085
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✦ Synopsis
Abstract
Four groups (I, II, III, and IV) of six Wistar rats each were studied to elucidate the blood pressure changes following creation of arteriovenous fistulae (AVF) of diameters 1, 2, and 3 mm (groups II, III, and IV, respectively). Group I comprised normal rats with no AVF. Blood pressures were recorded in the carotid and femoral arteries, the femoral and portal veins, the right atrium, and the inferior vena cava (IVC) at renal vein (RV) and common iliac vein (CIV) levels. We found that AVF size did not disturb baseline carotid arterial or portal venous pressures (P > 0.01), but that femoral arterial pressures fell increasingly (P < 0.01). On the other hand, right atrial pressure and that of IVC at RV and CIV levels rose substantially with increasing diameters of AVF (P < 0.01). It was concluded that an AVF of 1 mm diameter least upset the normal blood pressures in the vessels examined.