Arsenite pretreatment enhances the cytotoxicity of mitomycin C in human cancer cell lines via increased NAD(P)H quinone oxidoreductase 1 expression

Calcium and calcium sensing receptor mod

Calcium and calcium sensing receptor modulates the expression of thymidylate synthase, NAD(P)H:quinone oxidoreductase 1 and survivin in human colon carcinoma cells: Promotion of cytotoxic response to mitomycin C and fluorouracil

✍ Guangming Liu; Xin Hu; James Varani; Subhas Chakrabarty 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 272 KB

## Abstract Ca^2+^ and the cell‐surface calcium sensing receptor (CaSR) constitute a novel and robust ligand/receptor system in regulating the proliferation and differentiation of colonic epithelial cells. Here we show that activation of CaSR by extracellular Ca^2+^ (or CaSR agonists) enhanced the