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Arsenite-Induced Germline Apoptosis through a MAPK-Dependent, p53-independent Pathway in Caenorhabditis elegans

✍ Scribed by Pei, Bei; Wang, Shunchang; Guo, Xiaoyin; Wang, Jun; Yang, Gen; Hang, Haiying; Wu, Lijun


Book ID
121449914
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
188 KB
Volume
21
Category
Article
ISSN
0893-228X

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## BACKGROUND. Apoptosis is induced by various anticancer agents or radiation through the tumor suppressor gene p53-dependent pathway and is also induced by other factors, including transforming growth factor-PI (TGF-0,). In this study, the authors investigated whether TGF-0, would induce apoptosi