Arsenic trioxide inhibits cell proliferation and human papillomavirus oncogene expression in cervical cancer cells
β Scribed by Wang, Hongtao; Gao, Peng; Zheng, Jie
- Book ID
- 126837621
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 877 KB
- Volume
- 451
- Category
- Article
- ISSN
- 0006-291X
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## Abstract Arsenic trioxide (As~2~O~3~) is one of the arsenic compounds found in nature. As~2~O~3~ has recently been used to treat patients suffering from retinoic acid receptor (AML). It is of clinical interest to investigate whether As~2~O~3~ is also effective in treating solid tumors. Here, we
Arsenic trioxide (As 2 O 3 ), a major ingredient of arsenic compounds in traditional Chinese medicine, exhibits antiacute promyelocytic leukemic activity. Considering that over 80% of human malignant tumors derive from epithelial cells, we studied the effect of As 2 O 3 on HPV 16 DNA-immortalized hu