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Arsenic enhances the activation of Stat1 by interferon γ leading to synergistic expression of IRF-1

✍ Scribed by Chelbi-alix, Mounira K; Bobé, Pierre; Benoit, Gerard; Canova, Antony; Pine, Richard


Book ID
110068174
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
384 KB
Volume
22
Category
Article
ISSN
0950-9232

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## Abstract Recently, we reported that epidermal growth factor receptor (EGFR) induce expression of a module of genes known to be inducible by interferons and particularly interferon‐γ. Here we show that the module is tightly regulated by EGFR in the 2 human cancer cell lines that overexpress EGFR,