Four temperature-sensitive (ts) mutants of rat 3Y1 fibroblasts, representing independent complementation groups, cease to proliferate predominantly with a 2n DNA content, at the restrictive temperature (39.8OC)(temperature arrest) or at the permissive temperature (33.8OC) at a confluent cell density
โฆ LIBER โฆ
Arrest states in a set of mutants of rat 3Y1 cells temperature-sensitive for entering S phase
โ Scribed by Hirokazu Zaitsu; Genki Kimura
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 679 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0021-9541
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Proliferation of 3YltsF121 cells was arrested in GI and G2 phases after a shift up to 3 9 P C (restrictive temperature). Both arrests were reversible: after a shift down to 33.8OC (permissive temperature), these cells effectively entered the next phases. However, the entry into M phase of the G2-arr