Arrest of C1300 neuroblastoma cells by limiting serum or isoleucine: Implications for growth control in malignant cells

Nerve growth factor may stimulate either

Nerve growth factor may stimulate either division or differentiation of cloned C1300 neuroblastoma cells in serum-free cultures

✍ Roberto P. Revoltella; Richard H. Butler 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 620 KB

## Abstract Two clone of mouse C1300 neuroblastoma cells (clones NB1R and NB6R) bind mouse 2.5S Nerve Growth Factor (NGF) in vitro. The ligand is then capped and internalized by the cells. This step requires active cell processing. In serum‐free or low serum conditions, clear effects of NGF are see