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Arrest of -Amyloid Fibril Formation by a Pentapeptide Ligand

✍ Scribed by Tjernberg, L. O.; Naslund, J.; Lindqvist, F.; Johansson, J.; Karlstrom, A. R.; Thyberg, J.; Terenius, L.; Nordstedt, C.

Book ID
118009437
Publisher
The American Society for Biochemistry and Molecular Biology
Year
1996
Tongue
English
Weight
525 KB
Volume
271
Category
Article
ISSN
0021-9258

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## Abstract Caspase‐activated DNase (CAD) is a key protein in the process of apoptosis that degrades DNA through the action of caspases. Its N‐terminal region, the CAD domain (CAD‐CD), is highly conserved among CAD family proteins and is responsible for the interaction with its inhibitor. We report