Array-Based Sequence Capture and Next-Generation Sequencing for the Identification of Primary Immunodeficiencies
β Scribed by S. Ghosh; F. Krux; V. Binder; M. Gombert; T. Niehues; O. Feyen; H.-J. Laws; A. Borkhardt; on behalf of PID-NET: German Network on Primary Immunodeficiency Diseases
- Book ID
- 110862162
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 73 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0300-9475
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Nextβgeneration sequencing of large numbers of individuals presents challenges in data preparation, quality control, and statistical analysis because of the rarity of the variants. The Genetic Analysis Workshop 17 (GAW17) data provide an opportunity to survey existing methods and compar
Direct sequencing analysis is largely used to confirm and characterize mutations previously detected by more rapid tests. We have developed a method-Comparative Sequence Analysis (CSA)that simplifies the analysis of sequencing data facilitating its use as a first screen for mutation detection. Seque