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Arrangement of the ILT gene cluster: a common null allele of the ILT6 gene results from a 6.7-kbp deletion

✍ Scribed by Michaela Torkar; Anja Haude; Sarah Milne; Stephan Beck; John Trowsdale; Michael J. Wilson

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
191 KB
Volume
30
Category
Article
ISSN
0014-2980

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Familial growth hormone deficiency resul
Familial growth hormone deficiency resulting from a 7.6 kb deletion within the growth hormone gene cluster
✍ Braga, Suzanne ;Phillips, John A. ;Joss, Etienne ;Schwarz, Hanspeter ;Zuppinger, 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 608 KB

We report on two sibs with familial isolated growth hormone deficiency (IGHD) resulting from homozygosity for a 7.6 kb deletion within the growth hormone gene cluster. The deletion not only affects the structural gene for growth hormone (GH-N) but also alters sequences adjacent to the chorionic soma