𝔖 Bobbio Scriptorium
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Aromatic substitutions in α-conotoxin ImI.

✍ Scribed by Y.N Utkin; M.N Zhmak; C Methfessel; V.I Tsetlin

Book ID
117228764
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
156 KB
Volume
37
Category
Article
ISSN
0041-0101

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📜 SIMILAR VOLUMES

Cosolvent-assisted oxidative folding of
Cosolvent-assisted oxidative folding of a bicyclic α-conotoxin ImI
✍ Jacob S. Nielsen; Pawel Buczek; Dr Grzegorz Bulaj 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 114 KB

## Abstract α‐Conotoxin ImI is a 12‐amino acid peptide, found in the venom of the marine snail __Conus imperialis__. This conotoxin is a selective antagonist of α7 nicotinic acetylcholine receptors. To produce biologically active α‐ImI, disulfide bonds must be formed between Cys2–Cys8 and Cys3–Cys1