Aromatic iodination using N-iodosaccharin in room temperature ionic liquids

✍ Scribed by Lindsey Bailey; Scott T. Handy

• Publisher: Elsevier Science
• Year: 2011
• Tongue: French
• Weight: 214 KB
• Volume: 52
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2011.03.010

✦ Synopsis

More reactive iodination conditions have been developed that combine the use of room temperature ionic liquids with N-iodosaccharin. Using these reaction conditions, even very modestly activated arenes such as toluene can be iodinated in good yield under very mild conditions.