Aromatase and its inhibitors in breast cancer treatment — overview and perspective
✍ Scribed by Angela M. H. Brodie; Richard J. Santen
- Publisher
- Springer US
- Year
- 1994
- Tongue
- English
- Weight
- 535 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0167-6806
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Estrogens are the major hormones supporting the growth of human breast cancer. Aromatization of androgen precursors in peripheral tissues, including the breast cancer itself, is the major source of estrogens in postmenopausal women. Therefore, inhibition of the aromatase enzyme offers an effective m
Surgeons have been involved in the management of metastatic breast cancer since the technique of ovarian ablation was introduced in 1896. However, as newer hormonal and chemotherapeutic regimens were developed, drug therapy gradually replaced surgery as the preferred treatment for metastatic breast