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“Armed-disarmed” glycosidation strategy based on glycosyl donors and acceptors carrying phosphoroamidate as a leaving group: A convergent synthesis of globotriaosylceramide

✍ Scribed by Shun-ichi Hashimoto; Hiroki Sakamoto; Takeshi Honda; Hiroshi Abe; Sei-ichi Nakamura; Shiro Ikegami


Book ID
108386359
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
300 KB
Volume
38
Category
Article
ISSN
0040-4039

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Chemoselective glycosidation strategy ba
✍ Hiroki Sakamoto; Seiichi Nakamura; Toshifumi Tsuda; Shunichi Hashimoto 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 117 KB

A convergent synthesis of ganglioside GM 3 has been achieved by capitalizing on three different phosphorus-containing leaving groups, in which the key features involve a chemo-and regioselective a-glycosidation of sialyl phosphite with partially benzylated galactosyl tetramethylphosphorodiamidate by