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Argon laser micro-irradiation of mitochondria in rat myocardial cells in tissue culture

✍ Scribed by Michael W. Berns; Nicolai Gamaleja; Robert Olson; Cecilia Duffy; Donald E. Rounds

Publisher: John Wiley and Sons
Year: 1970
Tongue: English
Weight: 615 KB
Volume: 76
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1040760211

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✦ Synopsis

Abstract

Three types of lesions produced by argon laser micro‐irradiation of single mitochondria are described. A correlation between lesion severity and optical phase density and/or laser output power was observed. Cell survival was generally not affected by mitochondrial irradiation. As many as ten mitochondria were irradiated without cell death resulting. Absorption of the laser radiation was attributed to the natural chromophores, cytochromes c and c~1~.

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