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Arginine release from rat cerebellar astrocytes: autocrine roles for glutamate and nitric oxide?

✍ Scribed by Joanna Segieth; Leslie Fowler; Peter S. Whitton; Brian Pearce

Book ID
116767207
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
81 KB
Volume
372
Category
Article
ISSN
0304-3940

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## Abstract Nitric oxide (NO; 1 ΞΌM) or an NO donor (500 ΞΌM diethylenetriamine‐nitric oxide, DETA‐NONOate) caused rapid glutamate and ATP release from cultured rat cortical astrocytes. NO‐induced glutamate release was prevented by calcium chelators (EGTA or BAPTA‐AM) and an inhibitor of vesicular ex